Respiratory syncytial virus--how soon will we have a vaccine?
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چکیده
منابع مشابه
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Human respiratory syncytial virus (HRSV) is a major cause of severe respiratory tract illnesses in infants and young children worldwide. Despite its importance as a respiratory pathogen, there is currently no licensed vaccine for HRSV. Following failure of the initial trial of formalin-inactivated virus particle vaccine, continuous efforts have been made for the development of safe and efficaci...
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BACKGROUND Bronchiolitis caused by the respiratory syncytial virus (RSV) in infants less than two years old is a growing public health concern worldwide, and there is currently no safe and effective vaccine. A major component of RSV nucleocapsid, the nucleoprotein (N), has been so far poorly explored as a potential vaccine antigen, even though it is a target of protective anti-viral T cell resp...
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Respiratory syncytial virus (RSV) is a major cause of acute lower respiratory tract infection in infants, young children, and the elderly. Two subtypes of RSV, A and B, circulate alternately at 1-2-year intervals during epidemics. The attachment glycoprotein (G protein) of RSV is one of the major targets for immune responses. In this study, we generated a recombinant fusion protein, GcfAB, whic...
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Respiratory Syncytial Virus (RSV) is a major cause of severe lower respiratory tract infections in infants and children, leading to hospitalization of an estimated >3 million children under the age of 5 annually [1]. Despite such staggering figures, there is currently no licensed RSV vaccine. In the 1960s, a formalin-inactivated RSV vaccine candidate disastrously led to exacerbated disease [2]....
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1995
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.72.1.1